Oct 21, 2020 08:45
3 yrs ago
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English term

dose-dense fashion

English to Russian Medical Medical: Pharmaceuticals
With regards to the chemotherapy regimen following anthracyclines, a randomized controlled trial conducted by the Eastern Cooperative Oncology Group (ECOG) (N Engl J Med. 2008;358(16):1663) demonstrated that paclitaxel is more effective when used in a lower, dose-dense fashion.

The patient’s treating physician stated a chemotherapy programme comprising 4 cycles of dose-dense Doxorubicin dosed at 100mg/m2 and Cyclophosphamide dosed at 1000mg/m2 every 14 days.

Proposed translations

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51 mins
Selected

дозоуплотненный режим [химиотерапии]

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Peer comment(s):

agree svetlana cosquéric
2 hrs
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4 KudoZ points awarded for this answer. Comment: "Спасибо!"
53 mins

применение сниженных доз с большей частотой

..эффективность терапии паклитакселом выше при применении сниженных доз с большей частотой [по сравнению со стандартным режимом химиотерапии].

A chemotherapy treatment plan in which drugs are given with less time between treatments than in a standard chemotherapy treatment plan.
https://www.cancer.gov/publications/dictionaries/cancer-term...

By decreasing the dose and increasing the frequency, the fast growth can be prevented, allowing for faster and more effective cure rate. Although the dose is reduced in each treatment, the total quantity of chemotherapy may or may not be increased over the duration of the typical treatment time.
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