Glossary entry (derived from question below)
English term or phrase:
gene silencing
Finnish translation:
geenin hiljentäminen
Feb 9, 2010 13:59
14 yrs ago
English term
gene silencing
GBK
English to Finnish
Science
Biology (-tech,-chem,micro-)
Definition from
MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent.
The process of gene silencing is important for the differentiation of many different types of cells.
Example sentences:
Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. (biotech-info.net)
The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? (The Thomson Corporation)
In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. (ScienceDaily LLC)
Proposed translations
(Finnish)
5 +2 | geenin hiljentäminen | Antti Korhonen |
Change log
Feb 9, 2010 13:01: changed "Kudoz queue" from "In queue" to "Public"
Feb 9, 2010 13:59: changed "Stage" from "Preparation" to "Submission"
Feb 12, 2010 15:07: changed "Stage" from "Submission" to "Selection"
Mar 13, 2010 13:54: changed "Stage" from "Selection" to "Completion"
Proposed translations
+2
12 days
Selected
geenin hiljentäminen
Definition from
own experience or research:
Geenin hiljentäminen tarkoittaa geenin ilmenemisen estämistä organismin ilmiasussa, joko geenin koodauksen yhteydessä tai sen jälkeen.
Example sentences:
RNA-interferenssi teknologiaa käytettiin myös tutkittaessa PPM1D-geenin hiljentämisen vaikutuksia geenien ilmentymistasoihin sekä solujen prosesseihin. (Väitöskirjan tiedot Pärssinen Jenita)
BpMADS4-geenin hiljentäminen kyseessäolevalla menetelmällä myöhäisti kukkimisaikaa. (Koivun kukan kehityksen geneettinen sä�)
Peer comment(s):
agree |
Alfa Trans (X)
6 days
|
agree |
Arja Whiteside (X)
: tai geenihiljennys
19 days
|
4 KudoZ points awarded for this answer.
Discussion
http://fi.wikipedia.org/wiki/RNAi